Is Prilosec OTC Omeprazole 20mg (28 count) HSA or FSA Eligible?

Yes โ€” Prilosec OTC Omeprazole 20mg (28 count) is HSA and FSA eligible. No prescription or LMN required.

Eligibility status

HSA + FSA Eligible

HSA

Eligible

FSA

Eligible

LMN required

No

Last verified May 2026

๐Ÿ’Š

Prilosec OTC

Prilosec OTC Omeprazole 20mg (28 count)

Proton pump inhibitor for 24-hour frequent heartburn treatment โ€” take once daily for 14 days.

$22

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Eligibility verified May 2026 ยท IRS Pub 502

Why this eligibility status?

OTC proton pump inhibitors are qualified drug expenses under the CARES Act of 2020.

The full list of qualified medical expenses is defined in IRS Publication 502, updated annually. The CARES Act of 2020 expanded eligibility to include all OTC medicines and menstrual care products.

How to use HSA/FSA for this product

  1. Purchase Prilosec OTC Omeprazole 20mg (28 count) directly with your HSA or FSA debit card โ€” no pre-approval needed.
  2. Alternatively, pay out of pocket and submit the receipt for reimbursement through your plan's portal or app.
  3. Keep your receipt. If your card is declined (auto-substantiation failure), you can manually submit the receipt.
  4. Save receipts for 7 years in case of an IRS audit.

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