Is Ondansetron (Zofran) 4mg Tablets Rx HSA or FSA Eligible?
Yes — Ondansetron (Zofran) 4mg Tablets Rx is HSA and FSA eligible when accompanied by a Letter of Medical Necessity (LMN) from a licensed healthcare provider.
Eligibility status
HSA
Eligible
FSA
Eligible
LMN required
Yes
Last verified May 2026
Generic
Ondansetron (Zofran) 4mg Tablets Rx
Prescription ondansetron 4mg antiemetic for severe nausea and vomiting from motion sickness or GI illness during travel.
$20
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Why this eligibility status?
Prescription antiemetic medications are qualified medical expenses under IRS Publication 502. A valid prescription is required.
The full list of qualified medical expenses is defined in IRS Publication 502, updated annually. The CARES Act of 2020 expanded eligibility to include all OTC medicines and menstrual care products.
How to use HSA/FSA for this product
- Schedule an appointment with your doctor and discuss the medical condition you need to manage.
- Request a Letter of Medical Necessity (LMN) citing Ondansetron (Zofran) 4mg Tablets Rx by name.
- Purchase the product with your HSA/FSA debit card, or pay out of pocket.
- Submit your receipt + LMN through your plan administrator's portal.
- Save the documentation for at least 7 years for IRS records.
Letter of Medical Necessity required
Use our free template. Your doctor can sign it in 5 minutes.
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Frequently asked
Sources & last update
- IRS Publication 502 — Medical and Dental Expenses
- FSA Store Eligibility List
- CARES Act of 2020 — OTC Drug Expansion
Last updated: May 2026