Is Benadryl Original Strength 25mg 48-Count HSA or FSA Eligible?

Diphenhydramine HCl is an FDA-recognized OTC sleep aid; all OTC medicines became eligible under the CARES Act of 2020.

The full list of qualified medical expenses is defined in IRS Publication 502, updated annually. The CARES Act of 2020 expanded eligibility to include all OTC medicines and menstrual care products.

1. Purchase Benadryl Original Strength 25mg 48-Count directly with your HSA or FSA debit card — no pre-approval needed.
2. Alternatively, pay out of pocket and submit the receipt for reimbursement through your plan's portal or app.
3. Keep your receipt. If your card is declined (auto-substantiation failure), you can manually submit the receipt.
4. Save receipts for 7 years in case of an IRS audit.